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Syncope in pediatric patients presenting to an emergency department

Massin, M. M., Bourguignont, A., Coremans, C., Comté, L., Lepage, P., & Gérard, P. (2004). The Journal of pediatrics. Abstract Conclusions: Syncope in children can result from a wide variety of causes. Consequently, an evaluation that fails to approach this problem in a goal-directed fashion proves to be very expensive, time-consuming, and frustrating to all […]

Treatment of community-onset, childhood convulsive status epilepticus: a prospective, population-based study

Chin, R. F., Neville, B. G., Peckham, C., Wade, A., Bedford, H., & Scott, R. C. (2008). The Lancet Neurology. Abstract Conclusions: These data add to the debate on optimum emergency treatment of childhood CSE and suggest that the current guidelines could be updated.

Drug management for acute tonic-clonic convulsions including convulsive status epilepticus in children

Appleton, R., Macleod, S., & Martland, T. (2008). Cochrane Database Syst Rev. Abstract Conclusions: The conclusions of this update have changed to suggest that intravenous lorazepam is at least as effective as intravenous diazepam and is associated with fewer adverse events in the treatment of acute tonic-clonic convulsions. Where intravenous access is unavailable there is […]

Sickle-cell disease

Rees, D. C., Williams, T. N., & Gladwin, M. T. (2010). The Lancet. Summary: Sickle-cell disease is one of the most common severe monogenic disorders in the world. Haemoglobin polymerisation, leading to erythrocyte rigidity and vaso-occlusion, is central to the pathophysiology of this disease, although the importance of chronic anaemia, haemolysis, and vasculopathy has been […]

Intranasal medication delivery for children: a brief review and update

Wolfe, T. R., & Braude, D. A. (2010). Pediatrics. Abstract Conclusions: Intranasal medication delivery offers an alternative method of drug delivery that is often as fast in onset as intravenous medication, usually painless, inexpensive, easy to deliver, and effective in a variety of acute pediatric medical conditions. This article briefly reviews the most common uses […]