Roback MG, Wathen JE, Bajaj L, et al (2005). Academic Emergency Medicine. Abstract Conclusions: “Drug types used in pediatric PSA [pediatric sedation and analgesia] are associated with different adverse event profiles. Patients receiving ketamine with or without midazolam experienced fewer respiratory adverse events but more vomiting than the commonly used combination of midazolam and fentanyl. […]
Does midazolam alter the clinical effects of intravenous ketamine sedation in children? A double-blind, randomized, controlled, emergency department trial
Wathen JE, Roback MG, Mackenzie T, et al (2000). Annals of Emergency Medicine. Abstract Conclusions: “Ketamine and combined ketamine and midazolam provided equally effective sedation. The addition of midazolam did not alter the incidence of emergence phenomena. Vomiting occurred more frequently in the ketamine only group, whereas oxygen desaturation occurred more frequently in the ketamine-midazolam […]
Clinical policy: evidence-based approach to pharmacologic agents used in pediatric sedation and analgesia in the emergency department
Mace SE, Barata IA, Cravero JP, et al (2004). Journal of Emergency Nursing. No abstract available.
A trial of metoclopramide vs sumatriptan for the emergency department treatment of migraines
Friedman BW, Corbo J, Lipton RB, et al (2005). Neurology. Abstract Conclusions: “When compared at 2 and 24 hours, aggressive (20 mg dosed up to four times) IV metoclopramide and 6 mg of subcutaneous sumatriptan relieved migraine headache pain comparably. Some secondary endpoints suggest that metoclopramide may be the preferable therapy for migraines presenting to […]
Pediatric migraine
Lewis DW. Abstract (this is a review article): “Migraine headaches are common in children and adolescents, with a wide spectrum of clinical forms. The most frequent pattern in children is migraine without aura, characterized by attacks of frontal, pounding, nauseating headache lasting 1 to 72 hours. The spectrum of migraine with aura includes migraine with […]