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A comparison of oral dexamethasone with oral prednisone in pediatric asthma exacerbations treated in the ED

Greenberg RA, Kerby G, Roosevelt GE (2008). Clinical Pediatrics. Abstract Conclusions: “No difference was found in the relapse rate or incidence of vomiting between patients given prednisone and dexamethasone for pediatric asthma exacerbations.”

Nebulizers vs MDI with spacers for bronchodilator therapy to treat wheezing in children aged 2-24 months in the pediatric ED

Delgado A, Chou KJ, Silver EJ, Crain EF (2003). Archives of Pediatric Adolescent Medicine. Abstract Conclusions: “Our data suggest that metered-dose inhalers with spacers may be as efficacious as nebulizers for the emergency department treatment of wheezing in children aged 2 years or younger.”

Is nebulized aerosol treatment necessary in the pediatric emergency department?

Mandelberg A, Tsehori S, Houri S, Gilad E, Morag B, Priel I (2000). Chest. Abstract Conclusions: “We conclude that even in the group of unselected very young children (mean age < 2 years) with AWE [acute wheezing episodes], the use of MDI with NESD [non-electrostatic spacer device] is at least as effective as the use […]

Single-dose oral dexamethasone in the emergency management of children with exacerbations of mild to moderate asthma

Altamini S, Robertson G, Jastaniah W, Davey A, Dehghani N, Chen R, Leung K, Colbourn (2006). Pediatric Emergency Care. Abstract Conclusions: “A single dose of oral Dex (0.6 mg/kg) is no worse than 5 days of twice-daily prednisolone (1 mg/kg per dose) in the management of children with mild to moderate asthma.”

AOTW: Terbutaline in Asthma

by Alex Rucker MD Children’s National Early administration of terbutaline in severe pediatric asthma may reduce the need for assisted ventilation.  It’s from the March 2014 Annals of Allergy, Asthma and Immunology.  Location:  North Shore-LIJ Hypothesis:  Early administration of IV terb, prior to PICU admission, for severe asthma patients will prevent need for both noninvasive […]