Chin, R. F., Neville, B. G., Peckham, C., Wade, A., Bedford, H., & Scott, R. C. (2008). The Lancet Neurology. Abstract Conclusions: These data add to the debate on optimum emergency treatment of childhood CSE and suggest that the current guidelines could be updated.
Drug management for acute tonic-clonic convulsions including convulsive status epilepticus in children
Appleton, R., Macleod, S., & Martland, T. (2008). Cochrane Database Syst Rev. Abstract Conclusions: The conclusions of this update have changed to suggest that intravenous lorazepam is at least as effective as intravenous diazepam and is associated with fewer adverse events in the treatment of acute tonic-clonic convulsions. Where intravenous access is unavailable there is […]
Sickle-cell disease
Rees, D. C., Williams, T. N., & Gladwin, M. T. (2010). The Lancet. Summary: Sickle-cell disease is one of the most common severe monogenic disorders in the world. Haemoglobin polymerisation, leading to erythrocyte rigidity and vaso-occlusion, is central to the pathophysiology of this disease, although the importance of chronic anaemia, haemolysis, and vasculopathy has been […]
Intranasal medication delivery for children: a brief review and update
Wolfe, T. R., & Braude, D. A. (2010). Pediatrics. Abstract Conclusions: Intranasal medication delivery offers an alternative method of drug delivery that is often as fast in onset as intravenous medication, usually painless, inexpensive, easy to deliver, and effective in a variety of acute pediatric medical conditions. This article briefly reviews the most common uses […]
Is this child dehydrated?
Steiner, M. J., DeWalt, D. A., & Byerley, J. S. (2004). Jama. Abstract Conclusions: The initial assessment of dehydration in young children should focus on estimating capillary refill time, skin turgor, and respiratory pattern and using combinations of other signs. The relative imprecision and inaccuracy of available tests limit the ability of clinicians to estimate the […]